IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene AQP3 Ensembl ENSG00000165272 Chromosome 9 Start 33431161 End 33437590
Description Aquaporin-3 (AQP-3) [Source:UniProtKB/Swiss-Prot;Acc:Q92482]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 636
     Entrez Gene : 360
     UCSC : uc003zsx.2
     GeneCards : 636
     RefSeq : NM_004925
     CCDS : CCDS6542.1
     Uniprot : Q92482
     Interpro : Q92482
     OMIM : 600170
     GeneTests : AQP3
     CGAP : AQP3
     PMID : 7558005

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39248_at  -0.12  7.04e-1  7.81e-1  -1.07  3.53e-3  9.29e-3
 HG_U95  39249_at  -0.04  9.09e-1  9.34e-1  -0.96  2.89e-2  5.75e-2
 HG_U133A  203747_at  0.38  7.86e-3  1.25e-2  0.75  2.22e-18  3.16e-18
 HG_U133A  39248_at  0.24  1.74e-1  2.16e-1  -3.47  1.91e-124  2.63e-123
 HG_U133A  39249_at  1.02  1.31e-7  3.71e-7  0.27  2.32e-3  2.56e-3
 HG_U133_Plus2  203747_at  0.19  3.45e-1  4.34e-1  -0.28  2.47e-1  3.03e-1
 HG_U133_Plus2  39248_at  -0.72  4.40e-4  1.23e-3  -2.01  1.57e-14  1.17e-13
 HG_U133_Plus2  39249_at  -0.18  4.14e-1  5.04e-1  -0.89  5.98e-4  1.19e-3
 Stanford  15212  -0.47  5.18e-1  6.96e-1  -2.39  4.27e-4  7.72e-3
 Agilent_HS_21.6K  20842  -0.20  8.05e-2  2.02e-1  -0.31  1.18e-4  9.16e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203747_at  -0.01  9.90e-1  9.99e-1  0.16  6.52e-1  1.00e+0
 HG_U133A  39248_at  -0.42  5.02e-1  9.29e-1  0.04  9.25e-1  1.00e+0
 HG_U133A  39249_at  -0.15  8.26e-1  9.84e-1  -0.37  4.30e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39248_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 39249_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203747_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 39248_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 39249_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203747_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 39248_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 39249_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 15212    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20842    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
aqp3 tumor Immunohistochemistry was performed on serial cryostat sections of healthy parts of tumor nephrectomized human kidneys to study the distributions in the distal convolution of the thiazide-sensitive Na-Cl cotransporter (NCC), the beta subunit of the amilori 11912242 Human
aquaporin 3 tumor Immunohistochemistry was performed on serial cryostat sections of healthy parts of tumor nephrectomized human kidneys to study the distributions in the distal convolution of the thiazide-sensitive Na-Cl cotransporter (NCC), the beta subunit of the amilori 11912242 Human
aqp3 bronchogenic carcinoma Further in situ hybridization showed that expression of AQP1, AQP3, and AQP5 were detected in tumor-infiltrating lymphocytes surrounding bronchogenic carcinoma of the lung and that expression of AQP3 and AQP5 was detected in dendritic cells. 14978691 Human
aqp-3 cysts Among these AQP-positive cysts, more than 90% of the cysts were intensely stained, with well-polarized localization of AQP-2 and AQP-3. 9069455 Human
aqp-3 cysts In fewer than 10% of AQP-positive cysts, by contrast, immunostaining for AQP-2 and AQP-3 was faint and no clearly polarized localization of the channels was observed. 9069455 Human
aqp-3 cysts Moreover, staining specific for AQP-3 was observed in all of the AQP-2-positive cysts. 9069455 Human
aqp-3 renal tumors These results suggest that: (1) the trabecular and tubular variant of CDC with the urothelial AQP-3+, vimentin- phenotype can be included in the spectrum of urothelial diseases; (2) the papillary variant probably does not belong to the same entity; (3) AQ 15480763 Human
aquaporin-3 plasmacytoma To explore the possibility for giving accurate real time quantitative RT-PCR results, cDNA obtained from matched frozen, Bouin-fixed and formalin-fixed neoplastic samples (two diffuse large cell lymphomas, one plasmacytoma) was tested for the following ta 15507667 Human
aquaporin-3 diffuse large cell lymphomas To explore the possibility for giving accurate real time quantitative RT-PCR results, cDNA obtained from matched frozen, Bouin-fixed and formalin-fixed neoplastic samples (two diffuse large cell lymphomas, one plasmacytoma) was tested for the following ta 15507667 Human

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