IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene UBAP1 Ensembl ENSG00000165006 Chromosome 9 Start 34169011 End 34242520
Description Ubiquitin-associated protein 1 (UBAP)(Nasopharyngeal carcinoma-associated gene 20 protein) [Source:UniProtKB/Swiss-Prot;Acc:Q9NZ09]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 12461
     Entrez Gene : 51271
     UCSC : uc003ztx.2
     GeneCards : 12461
     RefSeq : NM_001171201
     CCDS : CCDS6550.1
     Uniprot : Q9NZ09
     Interpro : Q9NZ09
     OMIM : 609787
     GeneTests : UBAP1
     CGAP : UBAP1

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  221490_at  0.11  5.41e-2  7.47e-2  0.34  3.78e-9  4.67e-9
 HG_U133A  46270_at  0.13  2.68e-2  3.91e-2  0.13  1.50e-2  1.62e-2
 HG_U133_Plus2  221490_at  0.29  1.39e-4  4.29e-4  0.30  4.56e-3  7.88e-3
 HG_U133_Plus2  46270_at  0.18  1.17e-2  2.35e-2  0.12  2.20e-1  2.73e-1
 Agilent_HS_21.6K  9526  0.00  9.91e-1  9.95e-1  -0.02  4.85e-1  6.36e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  221490_at  -0.03  8.99e-1  9.94e-1  0.03  8.05e-1  1.00e+0
 HG_U133A  46270_at  0.11  6.14e-1  9.54e-1  -0.04  8.10e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 221490_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 46270_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 221490_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 46270_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9526    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ubap1 tumor Isolation and characterization of a novel cDNA, UBAP1, derived from the tumor suppressor locus in human chromosome 9p21-22. 11599797 Human
ubap1 tumor RESULTS: Database surveys indicated ubap1 gene was not only ubiquitously expressed in many normal tissues with various levels but also differentially expressed in different tumor tissues, especially down-regulated in multiple neoplastic tissues such as br 12451983 Human
ubap1 nasopharyngeal carcinoma (npc) [Identification of digital differential expression patterns of a novel human gene (UBAP1) by an expressed sequence tag strategy] BACKGROUND & OBJECTIVES: This study was designed to identify differential expression patterns in tumor and normal tissues of t 12451983 Human
ubap1 tumor [Identification of digital differential expression patterns of a novel human gene (UBAP1) by an expressed sequence tag strategy] BACKGROUND & OBJECTIVES: This study was designed to identify differential expression patterns in tumor and normal tissues of t 12451983 Human
ubap1 tumor Furthermore, differential RT-PCR was used to describe the expression patterns of ubap1 in partial tumor tissues. 12451983 Human
ubap1 colorectal tumor Furthermore, differential RT-PCR analysis demonstrated expression of ubap1 was down-regulated or absent in 7 of 11(64%) meningioma samples and 13 of 18 (72%) colorectal tumor tissues respectively. 12451983 Human
ubap1 meningioma Furthermore, differential RT-PCR analysis demonstrated expression of ubap1 was down-regulated or absent in 7 of 11(64%) meningioma samples and 13 of 18 (72%) colorectal tumor tissues respectively. 12451983 Human
ubap1 tumors CONCLUSIONS: The authors present an EST approach that proved to be useful for the identification of differential expression patterns of ubap1 in different tumors. 12451983 Human
ubap1 cancers These findings could be valuable for the investigation of the mechanism of UBAP1 gene exhibiting differential expression, potentially involved in the progression of multiple cancers. 12451983 Human
ubap1 nasopharyngeal carcinoma Purification of novel UBAP1 protein and its decreased expression on nasopharyngeal carcinoma tissue microarray. 16226037 Human
ubap1 nasopharyngeal carcinoma [Expression and location of UBAP1 protein associated with nasopharyngeal carcinoma] OBJECTIVE: To analyze the expression and location of coding protein of UBAP1 gene and to understand the relationship between the expression pattern of the protein and cell 16708796 Human
ubap1 npc [Identification of digital differential expression patterns of a novel human gene (UBAP1) by an expressed sequence tag strategy] BACKGROUND & OBJECTIVES: This study was designed to identify differential expression patterns in tumor and normal tissues of t 12451983 Human
ubap1 uterus tumor RESULTS: Database surveys indicated ubap1 gene was not only ubiquitously expressed in many normal tissues with various levels but also differentially expressed in different tumor tissues, especially down-regulated in multiple neoplastic tissues such as br 12451983 Human
ubap1 npc The present study aimed to explore the purification approach to UBAP1 protein and its expression pattern in NPC with tissue microarray. 16226037 Human
ubap1 npc With this antiserum, high-throughput analysis of UBAP1 protein expression using immunohistochemistry was performed on self-made tissue microarrays consisting of 316 nasopharyngeal specimens from 148 NPC and 168 non-cancerous nasopharyngeal epithelia with 16226037 Human
ubap1 npc Consequently, we found that there was a significant decrease in the percentage of positive expression in all NPC on protein levels for UBAP1 (23%), compared to that of the non-NPC (89%) (P<0.01). 16226037 Human
ubap1 malignant transformation The result suggests that UBAP1 might be a potential effective diagnosis candidate for NPC and decreased expression of UBAP1 protein is a possible point of dysfunction along the pathogenesis pathway for NPC that may contribute to malignant transformation. 16226037 Human
ubap1 npc The result suggests that UBAP1 might be a potential effective diagnosis candidate for NPC and decreased expression of UBAP1 protein is a possible point of dysfunction along the pathogenesis pathway for NPC that may contribute to malignant transformation. 16226037 Human
ubap1 carcinogenesis [Expression and location of UBAP1 protein associated with nasopharyngeal carcinoma] OBJECTIVE: To analyze the expression and location of coding protein of UBAP1 gene and to understand the relationship between the expression pattern of the protein and cell 16708796 Human
ubap1 nasopharyngeal carcinoma [Identification of digital differential expression patterns of a novel human gene (UBAP1) by an expressed sequence tag strategy] BACKGROUND & OBJECTIVES: This study was designed to identify differential expression patterns in tumor and normal tissues of t 12451983 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.