IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TESK1 Ensembl ENSG00000107140 Chromosome 9 Start 35595281 End 35600037
Description Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1)(Testicular protein kinase 1) [Source:UniProtKB/Swiss-Prot;Acc:Q15569]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 11731
     Entrez Gene : 7016
     UCSC : uc003zxa.2
     GeneCards : 11731
     RefSeq : NM_006285
     CCDS : CCDS6580.1
     Uniprot : Q15569
     Interpro : Q15569
     OMIM : 601782
     GeneTests : TESK1
     CGAP : TESK1
     PMID : 8537404

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Somatic Mutaions        (help)
Lung cancer Adenocarcinoma Squamous Cell Carcinoma
Unique Mutated Samples % Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
1 0.44 225 1 0.51 195 0 0.00 7
Sample datas
Sample Name Histology Subtype DNA Mutation Protein Mutation Mutation Description Zygosity Genomic Co-ordinates NCBI36 Pubmed
NCI-H2122 AD c.322A>C p.R108R Substitution - coding silent Unknown 9:35596083-3559608316140923

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37553_at  -0.10  1.81e-1  2.69e-1  -0.08  4.94e-1  5.96e-1
 HG_U133A  204106_at  -0.13  4.33e-2  6.08e-2  -0.05  5.43e-1  5.53e-1
 HG_U133_Plus2  204106_at  0.05  4.50e-1  5.40e-1  0.36  3.48e-4  7.19e-4
 Stanford  19737  -0.02  9.29e-1  9.63e-1  -0.32  4.41e-1  6.68e-1
 Agilent_HS_21.6K  10368  -0.21  3.31e-4  3.16e-3  -0.22  4.46e-4  2.77e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204106_at  0.17  3.96e-1  8.98e-1  -0.12  4.73e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37553_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204106_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204106_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 19737    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10368    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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