IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CREB3 Ensembl ENSG00000107175 Chromosome 9 Start 35722317 End 35727004
Description Cyclic AMP-responsive element-binding protein 3 (Luman protein)(Transcription factor LZIP-alpha) [Contains Processed cyclic AMP-responsive element-binding protein 3] [Source:UniProtKB/Swiss-Prot;Acc:O43889]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 2347
     Entrez Gene : 10488
     UCSC : uc003zxv.2
     GeneCards : 2347
     RefSeq : NM_006368
     CCDS : CCDS6588.1
     Uniprot : O43889
     Interpro : O43889
     OMIM : 606443
     GeneTests : CREB3
     CGAP : CREB3
     PMID : 9271389

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40849_s_at  0.12  1.51e-1  2.33e-1  -0.06  5.67e-1  6.62e-1
 HG_U133A  209432_s_at  0.27  8.69e-6  2.03e-5  1.66  5.22e-51  1.21e-50
 HG_U133_Plus2  209432_s_at  0.35  1.10e-7  5.80e-7  -0.05  6.43e-1  6.94e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209432_s_at  0.22  3.25e-1  8.83e-1  -0.29  1.51e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40849_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209432_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209432_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
lzip tumor Our findings suggest that LZIP might serve a novel cellular tumor suppressor function that is targeted by the HCV core. 10675342 Human

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