IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GNE Ensembl ENSG00000159921 Chromosome 9 Start 36204430 End 36248450
Description Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes UDP-N-acetylglucosamine 2-epimerase(EC 5.1.3.14)(Uridine diphosphate-N-acetylglucosamine-2-epimerase)(UDP-GlcNAc-2-epimerase);N-acetylmannosamine kinase(EC 2.7.1.60)(ManAc kinase)] [Source:UniProtKB/Swiss-Prot;Acc:Q9Y223]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 23657
     Entrez Gene : 10020
     UCSC : uc010mli.2
     GeneCards : 23657
     RefSeq : NM_001128227
     CCDS : CCDS6602.1
     Uniprot : Q9Y223
     Interpro : Q9Y223
     OMIM : 603824
     GeneTests : GNE
     CGAP : GNE
     PMID : 9305887

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36515_at  -0.13  1.18e-1  1.90e-1  -0.01  8.88e-1  9.22e-1
 HG_U133A  205042_at  -0.07  2.92e-1  3.44e-1  -0.16  1.58e-1  1.66e-1
 HG_U133_Plus2  205042_at  -0.07  4.60e-1  5.49e-1  -0.38  1.24e-3  2.36e-3
 Stanford  18443  -0.10  6.63e-1  8.02e-1  0.01  9.83e-1  9.93e-1
 Agilent_HS_21.6K  1867  0.02  8.33e-1  9.06e-1  -0.01  9.00e-1  9.40e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205042_at  0.25  2.56e-1  8.55e-1  0.10  5.48e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36515_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205042_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205042_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 18443    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1867    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ibm2 paget disease Hence, autosomal dominant inclusion body myopathy (HIBM), Paget disease of bone (PDB), and frontotemporal dementia (FTD) localizes to a 1.08-6.46 cM critical interval on 9p13.3-12 in the region of autosomal recessive IBM2. 11749051 Human
the gne protein cancer Here, we show that the GNE protein is expressed in various mammalian cells and tissues with highest levels found in cancer cells and liver. 15748884 Human
gne cancer Here, we show that the GNE protein is expressed in various mammalian cells and tissues with highest levels found in cancer cells and liver. 15748884 Human

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