IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SHB Ensembl ENSG00000107338 Chromosome 9 Start 37578417 End 38059249
Description SH2 domain-containing adapter protein B [Source:UniProtKB/Swiss-Prot;Acc:Q15464]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10838
     Entrez Gene : 6461
     UCSC : uc004aax.2
     GeneCards : 10838
     RefSeq : NM_003028
     CCDS : CCDS43806.1
     Uniprot : Q15464
     Interpro : Q15464
     OMIM : 600314
     GeneTests : SHB
     CGAP : SHB
     PMID : 7713524

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40614_at  -0.52  4.71e-3  1.22e-2  -0.59  2.59e-3  7.09e-3
 HG_U133A  204656_at  -0.03  7.45e-1  7.81e-1  1.71  7.29e-46  1.55e-45
 HG_U133A  204657_s_at  -0.04  5.19e-1  5.72e-1  0.53  4.04e-14  5.39e-14
 HG_U133_Plus2  1557458_s_at  -0.22  3.03e-2  5.44e-2  -0.38  1.06e-3  2.04e-3
 HG_U133_Plus2  204656_at  -0.22  2.92e-2  5.27e-2  -0.32  1.68e-2  2.64e-2
 HG_U133_Plus2  204657_s_at  0.07  5.47e-1  6.31e-1  0.26  5.80e-2  8.20e-2
 HG_U133_Plus2  230459_s_at  0.30  1.06e-1  1.61e-1  0.66  1.44e-3  2.70e-3
 HG_U133_Plus2  243595_at  -0.30  7.40e-2  1.18e-1  -0.61  2.98e-3  5.31e-3
 Stanford  6806  0.15  5.84e-1  7.46e-1  0.11  8.01e-1  9.08e-1
 Stanford  14584  0.83  9.98e-3  6.46e-2  0.53  1.19e-1  3.05e-1
 Agilent_HS_21.6K  921  -0.07  4.54e-1  6.35e-1  -0.18  3.56e-2  9.57e-2
 Agilent_HS_21.6K  1402  0.07  2.71e-1  4.56e-1  0.07  1.72e-1  3.08e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204656_at  0.56  2.72e-1  8.65e-1  -0.25  4.19e-1  1.00e+0
 HG_U133A  204657_s_at  -0.14  5.68e-1  9.45e-1  -0.09  5.81e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40614_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204656_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204657_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1557458_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204656_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204657_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230459_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 243595_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 6806    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 14584    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 921    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1402    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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