IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KANK1 Ensembl ENSG00000107104 Chromosome 9 Start 460291 End 736105
Description KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15)(Kidney ankyrin repeat-containing protein) [Source:UniProtKB/Swiss-Prot;Acc:Q14678]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 19309
     Entrez Gene : 23189
     UCSC : uc003zgn.1
     GeneCards : 19309
     RefSeq : NM_015158
     CCDS : CCDS6441.1
     Uniprot : Q14678
     Interpro : Q14678
     OMIM : 607704
     GeneTests : KANK1
     CGAP : KANK1
     PMID : 12133830

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37225_at  -0.56  1.05e-5  5.43e-5  -0.23  1.64e-1  2.47e-1
 HG_U133A  213005_s_at  -0.74  6.88e-21  5.76e-20  -0.10  1.99e-1  2.07e-1
 HG_U133A  216762_at  -0.58  1.49e-13  7.16e-13  -0.05  4.54e-1  4.64e-1
 HG_U133A  216763_at  -0.10  3.58e-1  4.12e-1  6.98  2.10e-150  7.15e-149
 HG_U133_Plus2  1565832_at  -0.92  3.01e-6  1.26e-5  -1.59  3.13e-12  1.80e-11
 HG_U133_Plus2  213005_s_at  -0.69  1.06e-12  1.09e-11  -0.57  3.46e-8  1.22e-7
 HG_U133_Plus2  216762_at  -0.38  4.55e-2  7.77e-2  0.08  7.10e-1  7.54e-1
 HG_U133_Plus2  216763_at  -0.27  1.51e-1  2.18e-1  -0.20  3.68e-1  4.29e-1
 HG_U133_Plus2  237162_at  1.06  1.21e-8  7.32e-8  1.05  1.96e-6  5.51e-6
 HG_U133_Plus2  238789_at  0.61  1.82e-9  1.22e-8  0.99  1.49e-14  1.12e-13

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  213005_s_at  0.35  8.90e-2  7.64e-1  -0.01  9.50e-1  1.00e+0
 HG_U133A  216762_at  0.19  5.93e-1  9.51e-1  0.02  9.03e-1  1.00e+0
 HG_U133A  216763_at  0.01  9.83e-1  9.99e-1  0.14  6.11e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37225_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213005_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216762_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216763_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1565832_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213005_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216762_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216763_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 237162_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 238789_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kank renal-cell carcinoma A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma. 12133830 Human
kank renal-cell carcinoma By a combination of genome subtraction and comprehensive analysis of loss of heterozygosity based on mapping hemizygous deletions for a potential tumor-related locus, a minimum overlapping region of deletions at 9p24 the size of 165 kb was identified and 12133830 Human
kank tumor By a combination of genome subtraction and comprehensive analysis of loss of heterozygosity based on mapping hemizygous deletions for a potential tumor-related locus, a minimum overlapping region of deletions at 9p24 the size of 165 kb was identified and 12133830 Human
kank human tumor VAB-19 is a member of a conserved family of ankyrin repeat-containing proteins that includes the human tumor suppressor Kank. 14534136 Human

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