IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GNA14 Ensembl ENSG00000156049 Chromosome 9 Start 79228369 End 79453043
Description Guanine nucleotide-binding protein subunit alpha-14 (G-protein subunit alpha-14)(G alpha-14) [Source:UniProtKB/Swiss-Prot;Acc:O95837]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 4382
     Entrez Gene : 9630
     UCSC : uc004aku.2
     GeneCards : 4382
     RefSeq : NM_004297
     CCDS : CCDS6657.1
     Uniprot : O95837
     Interpro : O95837
     OMIM : 604397
     GeneTests : GNA14
     CGAP : GNA14
     PMID : 10191087

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220108_at  -0.22  4.60e-2  6.43e-2  -2.14  1.03e-58  2.73e-58
 HG_U133_Plus2  220108_at  -0.52  4.31e-4  1.21e-3  -1.75  2.69e-22  4.86e-21
 HG_U133_Plus2  243580_at  -0.01  9.75e-1  9.82e-1  -0.38  1.02e-1  1.37e-1
 Agilent_HS_21.6K  20339  -0.17  1.02e-2  4.64e-2  -0.28  2.29e-5  2.29e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  220108_at  0.16  6.80e-1  9.66e-1  -0.53  5.33e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 220108_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 220108_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 243580_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20339    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
gna14 all Subsequently, DNA methylation of 15 of these genes (GIPC2, RSPO1, MAGI1, CAST1, ADCY5, HSPA4L, OCLN, EFNA5, MSX2, GFPT2, GNA14, SALL1, MYO5B, ZNF382 and MN1) was validated in primary ALL samples. 18528427 Human
gna14 hcc Type III (4%, e.g. GNA14) shows decreased methylation in adjacent tissue but either similar or increased methylation in HCC. 18632756 Human

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