IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PTPRD Ensembl ENSG00000153707 Chromosome 9 Start 8304246 End 9008735
Description Receptor-type tyrosine-protein phosphatase delta Precursor (Protein-tyrosine phosphatase delta)(R-PTP-delta)(EC 3.1.3.48) [Source:UniProtKB/Swiss-Prot;Acc:P23468]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9668
     Entrez Gene : 5789
     UCSC : uc003zkk.2
     GeneCards : 9668
     RefSeq : NM_001040712
     CCDS : CCDS6472.1
     Uniprot : P23468
     Interpro : P23468
     OMIM : 601598
     GeneTests : PTPRD
     CGAP : PTPRD
     PMID : 7896816

< Top >


Somatic Mutaions        (help)
Lung cancer Adenocarcinoma Squamous Cell Carcinoma
Unique Mutated Samples % Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
10 5.03 199 9 4.76 189 0 0.00 0
Sample datas
Sample Name Histology Subtype DNA Mutation Protein Mutation Mutation Description Zygosity Genomic Co-ordinates NCBI36 Pubmed
16608 AD c.1448T>A p.V483E Substitution - Missense Heterozygous 9:8507943-850794318948947
16628 AD c.3770C>G p.P1257R Substitution - Missense Heterozygous 9:8450516-845051618948947
16686 AD c.1204G>T p.G402W Substitution - Missense Heterozygous 9:8508187-850818718948947
16835 AD c.1009A>G p.T337A Substitution - Missense Heterozygous 9:8508382-850838218948947
16857 AD c.3107T>A p.L1036Q Substitution - Missense Heterozygous 9:8475273-847527318948947
17288 AD c.1750C>A p.R584S Substitution - Missense Heterozygous 9:8494333-849433318948947
17298 AD c.5109T>G p.S1703R Substitution - Missense Heterozygous 9:8331107-833110718948947
17320 AD c.4607G>T p.R1536L Substitution - Missense Heterozygous 9:8365990-836599018948947
17330 AD c.5426C>G p.P1809R Substitution - Missense Heterozygous 9:8321690-832169018948947

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  1256_at  -0.14  4.00e-1  5.06e-1  -0.15  6.09e-1  7.00e-1
 HG_U95  33910_at  -1.78  6.21e-9  6.59e-8  -1.04  7.07e-4  2.28e-3
 HG_U95  33911_at  -1.25  1.83e-10  2.63e-9  -0.88  1.28e-3  3.85e-3
 HG_U133A  205712_at  -0.61  1.80e-8  5.53e-8  1.61  1.92e-33  3.36e-33
 HG_U133A  213362_at  -1.42  8.36e-44  2.94e-42  1.49  6.30e-47  1.36e-46
 HG_U133A  214043_at  -1.73  3.28e-35  6.95e-34  -0.52  1.55e-10  1.96e-10
 HG_U133A  216214_at  -0.30  3.85e-2  5.47e-2  -1.66  3.50e-16  4.81e-16
 HG_U133_Plus2  1566469_at  -0.37  1.17e-1  1.76e-1  -0.02  9.24e-1  9.39e-1
 HG_U133_Plus2  1567860_at  0.78  5.72e-4  1.56e-3  0.55  2.65e-2  3.99e-2
 HG_U133_Plus2  205712_at  0.09  6.17e-1  6.94e-1  0.81  1.83e-4  3.93e-4
 HG_U133_Plus2  213362_at  -1.86  5.18e-23  1.66e-21  -1.35  2.75e-8  9.81e-8
 HG_U133_Plus2  214043_at  -1.82  2.30e-20  5.59e-19  -1.38  5.62e-9  2.19e-8
 HG_U133_Plus2  216214_at  -0.39  3.19e-2  5.69e-2  -0.44  2.40e-2  3.64e-2
 HG_U133_Plus2  242493_at  0.51  3.63e-2  6.36e-2  0.36  2.01e-1  2.52e-1
 Stanford  13383  -0.54  1.01e-1  2.50e-1  0.02  9.43e-1  9.76e-1
 Agilent_HS_21.6K  17918  -0.05  1.24e-1  2.73e-1  -0.01  8.64e-1  9.17e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205712_at  0.13  7.26e-1  9.72e-1  -0.36  1.71e-1  1.00e+0
 HG_U133A  213362_at  -0.19  5.13e-1  9.34e-1  -0.03  8.93e-1  1.00e+0
 HG_U133A  214043_at  0.55  3.50e-1  8.90e-1  0.06  8.80e-1  1.00e+0
 HG_U133A  216214_at  -0.40  3.49e-1  8.88e-1  -0.42  1.31e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 1256_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 33910_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 33911_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205712_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213362_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214043_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216214_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1566469_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1567860_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205712_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213362_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214043_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216214_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 242493_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13383    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 17918    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.