IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ISCA1 Ensembl ENSG00000135070 Chromosome 9 Start 88069287 End 88087273
Description Iron-sulfur cluster assembly 1 homolog, mitochondrial Precursor (HESB-like domain-containing protein 2)(Iron sulfur assembly protein IscA)(hIscA) [Source:UniProtKB/Swiss-Prot;Acc:Q9BUE6]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 28660
     Entrez Gene : 81689
     UCSC : uc004aop.2
     GeneCards : 28660
     RefSeq : NM_030940
     CCDS : CCDS35056.1
     Uniprot : Q9BUE6
     Interpro : Q9BUE6
     OMIM : 611006
     GeneTests : ISCA1
     CGAP : ISCA1
     PMID : 15262227

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41147_at  -0.39  2.04e-4  7.69e-4  -0.24  7.47e-2  1.28e-1
 HG_U133A  209273_s_at  -0.10  4.78e-2  6.67e-2  0.39  6.40e-10  8.01e-10
 HG_U133A  209274_s_at  -0.32  2.71e-6  6.67e-6  -3.17  9.02e-106  7.13e-105
 HG_U133A  221425_s_at  0.18  6.34e-3  1.02e-2  -4.42  9.17e-62  2.56e-61
 HG_U133_Plus2  209273_s_at  0.08  3.26e-1  4.15e-1  0.38  2.48e-4  5.22e-4
 HG_U133_Plus2  209274_s_at  -0.28  9.58e-5  3.05e-4  -0.31  2.06e-3  3.76e-3
 HG_U133_Plus2  221425_s_at  -0.14  3.11e-1  3.99e-1  0.12  4.59e-1  5.20e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209273_s_at  -0.11  5.47e-1  9.38e-1  0.02  9.02e-1  1.00e+0
 HG_U133A  209274_s_at  0.36  1.19e-1  7.87e-1  0.16  4.74e-1  1.00e+0
 HG_U133A  221425_s_at  0.79  1.95e-2  6.83e-1  0.08  6.00e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41147_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209273_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209274_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 221425_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209273_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209274_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 221425_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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