IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene OGN Ensembl ENSG00000106809 Chromosome 9 Start 94186070 End 94206758
Description Mimecan Precursor (Osteoglycin)(Osteoinductive factor)(OIF) [Source:UniProtKB/Swiss-Prot;Acc:P20774]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8126
     Entrez Gene : 4969
     UCSC : uc004asa.2
     GeneCards : 8126
     RefSeq : NM_014057
     CCDS : CCDS6695.1
     Uniprot : P20774
     Interpro : P20774
     OMIM : 602383
     GeneTests : OGN
     CGAP : OGN
     PMID : 2372374

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218730_s_at  -2.61  6.03e-29  8.75e-28  2.50  3.33e-40  6.47e-40
 HG_U133_Plus2  218730_s_at  -3.20  7.03e-25  2.75e-23  -4.27  2.22e-30  1.08e-28
 HG_U133_Plus2  222722_at  -3.27  3.76e-31  2.96e-29  -4.13  2.49e-32  1.51e-30
 Stanford  16218  -1.14  1.25e-2  7.43e-2  -1.57  5.88e-4  9.65e-3
 Stanford  22087  -1.31  1.82e-3  2.15e-2  -1.11  3.66e-3  3.44e-2
 Agilent_HS_21.6K  20279  -0.39  1.42e-14  2.62e-12  -0.44  4.99e-14  8.37e-12

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218730_s_at  1.07  1.11e-1  7.80e-1  -0.23  6.33e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 218730_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218730_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 222722_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 16218    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22087    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20279    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
mimecan cancer In addition, we show absence of mimecan expression in different tumors and cancer cell lines, where p53 frequently is inactivated/mutated. 11342211 Human
mimecan tumors In addition, we show absence of mimecan expression in different tumors and cancer cell lines, where p53 frequently is inactivated/mutated. 11342211 Human
oif osteosarcoma The polymerase chain reaction was used to obtain clones coding for human OIF from the osteosarcoma cell line, MG-63. 2372374 Human
osteoglycin cancer Interestingly, the expression of several genes, such as osteoglycin, prostate stem cell antigen, and histone deacetylase 3, was variable in the two normal tissues but similar in the cancer tissues. 12809678 Human

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