IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NINJ1 Ensembl ENSG00000131669 Chromosome 9 Start 94923601 End 94936391
Description Ninjurin-1 (Nerve injury-induced protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q92982]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7824
     Entrez Gene : 4814
     UCSC : uc004atg.3
     GeneCards : 7824
     RefSeq : NM_004148
     CCDS : CCDS6703.1
     Uniprot : Q92982
     Interpro : Q92982
     OMIM : 602062
     GeneTests : NINJ1
     CGAP : NINJ1
     PMID : 8780658

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41475_at  -0.51  3.30e-2  6.49e-2  -1.10  6.12e-4  2.01e-3
 HG_U133A  203045_at  -0.07  3.37e-1  3.92e-1  1.61  7.36e-55  1.81e-54
 HG_U133_Plus2  203045_at  -0.12  1.21e-1  1.80e-1  -0.33  7.40e-3  1.24e-2
 Stanford  22178  0.02  9.40e-1  9.68e-1  -0.25  5.10e-1  7.23e-1
 Agilent_HS_21.6K  13486  -0.21  2.93e-3  1.80e-2  -0.29  1.74e-4  1.26e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203045_at  -0.16  4.03e-1  9.02e-1  -0.33  1.14e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41475_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203045_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203045_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22178    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 13486    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ninjurin human hepatocellular carcinoma Up-Regulation of ninjurin expression in human hepatocellular carcinoma associated with cirrhosis and chronic viral hepatitis. 11355694 Human
ninjurin liver tumor The intensity of immunohistochemical staining of the liver tumor tissue, and regenerating tissue for the ninjurin protein, was stronger than that of normal liver tissue. 11355694 Human
ninjurin hcc One of the clones, ninjurin (nerve injury induced protein), showed a much higher expression level in the liver tissue of HCC patients than in normal liver tissue. 11355694 Human
ninjurin hcc Interestingly, the presence of ninjurin mRNA transcripts was detected with high intensity in HCC tissues when combined with viral infection and cirrhosis, but not with a normal liver or HCC tissue unrelated with viral infection and cirrhosis. 11355694 Human
ninjurin hcc These results suggest that ninjurin may play an important role in the development of HCC combined with cirrhosis and viral infection. 11355694 Human
ninjurin1 human hepatoma Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells. 15464245 Human
ninjurin1 hepatoma METHODS: The effect of ninjurin1 overexpression was examined in Huh-7 hepatoma cells. 15464245 Human
ninjurin1 human hepatocellular carcinoma Ninjurin1 expression was examined by Western blot in human hepatocellular carcinoma tissues as well as their adjacent liver tissues. 15464245 Human
ninjurin1 hepatocellular carcinoma The levels of ninjurin1 expression were higher in hepatocellular carcinoma tissues than those in adjacent liver tissues. 15464245 Human

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