IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene HSD17B3 Ensembl ENSG00000130948 Chromosome 9 Start 98037410 End 98104255
Description Testosterone 17-beta-dehydrogenase 3 (EC 1.1.1.64)(Testicular 17-beta-hydroxysteroid dehydrogenase)(17-beta-HSD 3) [Source:UniProtKB/Swiss-Prot;Acc:P37058]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 5212
     Entrez Gene : 3293
     UCSC : uc004awa.1
     GeneCards : 5212
     RefSeq : NM_000197
     CCDS : CCDS6716.1
     Uniprot : P37058
     Interpro : P37058
     OMIM : 605573
     GeneTests : HSD17B3
     CGAP : HSD17B3
     PMID : 8075637

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39978_at  0.35  3.36e-2  6.59e-2  -0.31  3.06e-1  4.09e-1
 HG_U133A  206985_at  -0.47  3.62e-6  8.83e-6  4.06  1.11e-120  1.37e-119
 HG_U133_Plus2  206985_at  -0.10  5.87e-1  6.67e-1  0.78  1.51e-3  2.81e-3
 Stanford  14441  -0.47  5.40e-2  1.64e-1  -0.29  3.16e-1  5.57e-1
 Agilent_HS_21.6K  10243  -0.07  4.31e-1  6.14e-1  0.00  9.87e-1  9.93e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206985_at  0.19  6.78e-1  9.66e-1  -0.03  9.33e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39978_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206985_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206985_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 14441    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10243    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
hsd17b3 prostate cancer Association of the G289S single nucleotide polymorphism in the HSD17B3 gene with prostate cancer in Italian men. 12210481 Human
hsd17b3 prostate cancer METHODS: We have investigated the G289S (glycine at codon 289 replaced by serine) polymorphism at the HSD17B3 locus as a candidate single nucleotide polymorphism (SNP) for prostate cancer risk in constitutional DNA from 103 Italian prostate cancer patient 12210481 Human
hsd17b3 prostate cancer Therefore, the HSD17B3 gene may be a plausible candidate gene for prostate cancer risk. 12210481 Human

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