Quick Examples
ERBB2 - (chr) (gene)
EGFR - (chr) (gene)
hsa-let-7e - (chr) (miRNA)
hsa-mir-17 - (chr) (miRNA)
hsa-mir-31 - (chr) (miRNA)
Quick Search
Search a gene or miRNA:

( ex: TP53 or hsa-mir-200b )


Map of Significant Genes
AD : Gene AD      SCC : Gene SCC
Map of Significant miRNAs
AD : miRNA AD      SCC : miRNA SCC
Advanced search
( ex: Chromosome "20", "14q13.3" or others )
( ex: "Gene Name", "Accession number", "Gene ID", "Marker" or others )

Citation
To cite IGDB.NSCLC:
Kao S, Shiau CK, Gu DL, Ho CM, Su WH, Chen CF, Lin CH, Jou YS. IGDB.NSCLC: Integrated Genomic Database of Non-Small Cell Lung Cancer, Nucleic Acids Res. 2012 Jan 1; 40(D1): D972- D977.

PubMed Link
NAR Link

Statistics
General Data
Database Last Modified on : June 20 2011
Ensembl version : v.54 May 2009
Microarray Data
Unique Gene Numbers : 8472 (HG_U95A), 12315 (HG-U133A), 20415 (HG-U133_Plus_2), 11426 (Agilent Homo sapiens 21.6K), and 4743 (Stanford);
Sample Numbers : 1099 (AD) + 295 (SCC) + 189 (Normal)
Blast Database : Ensembl Human Release v.54.36p May 2009
Copy Number Alteration Data
Datasets : 5 ( Weir, GSE17958, HapMap, GSE12280, and GSE16597)
Unique Probeset Numbers : 212309 (Affymetrix Mapping 250K Sty2 SNP Array), 6210 (UMCG 6.5KBAC ARRAY), and 4044 (MacArary Karyo 4000)
Sample Numbers : 191 (AD) + 117(SCC) + 271 (Normal)
miRNA Data
Datasets : 2 (GSE15201 and GSE18692)
Unique miRNA Numbers : 163 (CCDTM miRNA700-V3) and 341 (IPMC - microRNA v4 and IPMC - microRNA v5LNA)
Sample Numbers : 193 (AD) + 137(SCC)
Mutated gene Data
Source : COSMIC
Unique mutated gene numbers : 1112 (lung) (AD - 386; SCC - 55)
Unique Sample Numbers : 12870 / 61210 (lung) (AD - 6898 / 24284 and SCC - 757 / 6965)
(Unique mutated sample numbers / total Unique sample numbers)
Paired (U133A/aCGH) AD Sample Data
Sample Numbers : Agilent_44K_aCGH(199 samples) / Affy_U133A (91 samples) / Affy_U133A2 (102 samples)
Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result
Sample Numbers : 17 + 11 = 28 (treatments + observations = AD) / 27 + 25 = 52 (treatments + observations = SCC)
Experimental Evidence Data
Reference numbers with experimental evidence: 221
Gene numbers with experimental evidence : 214
Chromosome Aberration Data
LOH reference number : 7
CGH reference number :11
Population information of NSCLC samples

MeyersonBoston, USA
GSE2514COMIRB, University of Colorado Denver, USA
GSE4573University of Michigan Hospital, USA (111 white / 2 black / 17 unknow)
GSE7670Taipei Veterans General Hospital, Taiwan
GSE10072The Environment And Genetics in Lung cancer Etiology (EAGLE) study (13 hospitals)
GSE17475University Hospital Freiburg, Germany
DCLungStudy6 Asian / 13 Black or African American / 327 White / 132Unknown
GSE3141Duke University, USA
GSE10245Heidelberg, Germany
GSE10445Hôtel-Dieu Hospital, France
GSE10799University Medical Center Hamburg-Eppendorf, Germany
GSE12667Tumour Sequencing Project (TSP), USA
GSE19188Erasmus MC, Netherlands
GSE3398not provided
GSE11969Aichi Cancer Center, Nagoya, Japan
WeirTumour Sequencing Project (TSP)
GSE17958not provided
HapMapthe CEU HapMap samples
GSE12280not provided
GSE16597the Chungnam National University Hospital, Korea
GSE15201The Environment And Genetics in Lung cancer Etiology (EAGLE) study
GSE18692Nice Hospital, France
COSMICnot provided
GSE14814Canada
Paired sample dataMemorial Sloan-Kettering Cancer Center, New York, USA